Took me a while to figure out what all the ESMFold2 rage was about. At first, the benchmarking data didn't look super remarkable to me but it turns there are many impressive aspects: - Fully open source, open weights + massive ESM Atlas (1.1B structures vs 0.2B for AF3).- SOTA performance despite no MSA use. MSA search and triangular attention were simply taken out of the base model.- Direct consequence, super low latency inference: 1024-residue protein structure prediction in 9 secs, still outp

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