Single-cell barcoding and deep-sequencing technologies have conspired to enable highly scalable analysis of DNA or RNA with unprecedented resolution 1,2,3. Transcriptional states, regulatory networks ...

DNA damage is a threat to genome integrity and can be a cause of many human diseases, owing to either changes in the chemical structure of DNA or conversion of the damage into a mutation, that is, a ...

Stay up to date on the latest science with Brush Up Summaries. Article reviewed by Ninning Liu, PhD from the Wyss Institute at Harvard University. Similar to retail stores that use standardized ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...