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T 细胞受体组库、CyTOF、基因分型及症状学数据整合揭示 COVID-19 患者 ...
为揭示 COVID-19 临床结局差异机制,研究人员整合 CyTOF、TCRseq、ACE2 等基因 SNPs 及症状数据,对 61 例患者行 LCM-BIC 聚类。发现 3 个新亚群,其中 Cluster 1 富集重症,具独特免疫特征,为 COVID-19 分层管理提供新方向。 新冠病毒(SARS-CoV-2)感染引发的 COVID-19 临床表现 ...
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