The actions of the commonly prescribed oral bisphosphonates are discussed. The groups of patients most likely to present in primary care with an oral bisphosphonate associated osteonecrosis of the ...

Long-term treatment with a bisphosphonate degrades fracture-resistance–toughening mechanisms that contribute to healthy bone, setting the stage for the rare but catastrophic risk of patients ...

Bisphosphonates may protect from breast cancer, suggest two studies published in a recent issue of the Journal of Clinical Oncology. In 2009, the bisphosphonate zoledronic acid was evaluated for its ...

Please provide your email address to receive an email when new articles are posted on . Among South-East Asian adults, bisphosphonate use in is not associated with differences in clinical outcomes or ...

Simon et al reviewed the skeletal consequences of discontinuing HT and the specific treatment options for these women. [12] This analysis included 11 RCTs that reported data on BMD changes during and ...

Directing Surgical Quality Improvement Initiatives: Comparison of Perioperative Mortality and Long-Term Survival for Cancer Surgery Osteonecrosis of the jaws (ONJ) was initially described in 2001 in ...

Studies show conflicting results regarding the possible excess risk of atypical fractures of the femoral shaft associated with bisphosphonate use. In Sweden, 12,777 women 55 years of age or older ...

Background: There have been several published reports of inflammatory ocular adverse events, mainly uveitis and scleritis, among patients taking oral bisphosphonates. We examined the risk of these ...

The FDA analyses looked at a composite end point of all fractures, both vertebral and nonvertebral, and showed little benefit of continued bisphosphonate treatment beyond 5 years. The original ...

Evaluation of the Tyrer-Cuzick (International Breast Cancer Intervention Study) Model for Breast Cancer Risk Prediction in Women With Atypical Hyperplasia The association between oral bisphosphonate ...

Nonsteroidal anti-inflammatory drugs (NSAIDs) seemed to neutralize the protective benefit of a certain bisphosphonate, according to a post-hoc analysis of a randomized controlled trial. Among over ...

Denosumab is a different type of medicine. It's a type of bone targeted treatment called a monoclonal antibody. You might have this as a treatment for cancer that has spread to the bones. It helps to ...